Enduring Hearts funds innovative, cutting-edge pediatric heart transplant research targeted but not limited to the following focal areas:
Transplant Longevity – Identification of early, accurate onset of rejection, development of non-invasive methods to detect rejection, strategies, and techniques to improve long-term graft survival.
Technology Application – Development of new technologies or technological applications that would improve the care and outcomes of transplant recipients
Transplant Immunology – Research and development of novel immunotherapies, identification of novel targets, improving the side-effect profiles of these agents, as well as better monitoring and measurement of immunosuppression.
Organ Matching – Strategies and innovations that would allow better organ matching and allocation.
Nutrition and Exercise Physiology – Development of evidence for pediatric heart recipient nutrition and exercise guidelines that improve the long-term outcomes of pediatric heart transplant recipients.
Medication Compliance – Development of evidence-based strategies to improve adherent behaviors, including medication compliance, especially in adolescent recipients.
Education – Improving patient and family education, related to transplantation.
Pre-Transplant Strategies – Utilizing the latest innovations or new technologies that would improve outcomes for children leading up to and after they receive a heart transplant.
Additional weighting is afforded to those research studies that have the potential to translate within the next five years, directly involves pediatric heart transplant recipients and their families and would promote the standardization of post-transplant care.